| EXPERIMENTAL WORK | |
| 1. | Effects of remifentanil and fentanyl on postoperative pain and recovery in fast – tract cardiac surgery Sema Turan, İhsan Ayık, Dilek Öztürk, Umit Karadeniz, Ozlem Soyal, Ahmet Coşar, Aysegul Ozgok, Ozcan Erdemli doi: 10.5222/GKDAD.2012.087 Pages 80 - 87 (1625 accesses) OBJECTIVE: The effectiveness of remifentanil infusion and fentanyl bolus provided by the patient-controlled analgesia on postoperative pain and recovery of the patients undergoing pre-planned fast-tract cardiac surgery was studied. METHODS: The anaesthesia including sevofluran and remifentanil were applied to 42, ASA II group patients undergoing fast –track coronary arter bypass graft surgery. Patients were divided into two groups. In Group 1 (remifentanil group), 0.1 µg kg-1 min-1 remifentanil infusion was given postoperatively by patient controlled analgesia device. In Group 2, fentanyl was administered at 10 µg kg-1 loading dose 5 minutes before the end of the surgery. After fentanyl administration, fentanyl bolus protocol was started at 0.1 µgkg-1 bolus dose with 8 minutes lockout time. Pain scores, sedation levels and additional analgesic requirements were recorded for the first 4 hours period in every 15 minutes and then 12th. and 24 th. hours postoperatively. RESULTS: There was no difference between the groups at the analgesic effectiveness. The sedation levels were lower postoperatively first two hours in Group 1. After two hours, sedation levels were similar in two groups. CONCLUSION: Remifentanil can be used at analgesic doses in recovery of patients undergoing fast-tract cardiac surgery. |
| 2. | The Effects of Esmolol on Hemodynamic Parameters and Total Remifentanil Consumption in Off-Pump CABG Patients Yasemin Polat Ünaltekin, Seyhan Yağar, Ayşegül Özgök doi: 10.5222/GKDAD.2012.088 Pages 88 - 95 (1632 accesses) OBJECTIVE: This study was designed to study the hemodynamic effects of esmolol infusion in off-pump CABG patients. METHODS: 34 ASA 2-3 adult patients scheduled for elective off-pump CABG surgery were randomly allocated to receive remifentanil+sevoflurane or remifentanil+sevoflurane with esmolol infusion. Patients were compared for hemodynamic changes (arterial blood pressure, heart rate, cardiac output, stroke volume), and total remifentanil consumption. RESULTS: The esmolol group had a better control of hemodynamics during all operation period. CONCLUSION: We concluded that esmolol would administer to anesthetics for better hemodynamic control in CABG patients. |
| 3. | Effects of Dexmedetomidine Sedation Combined with Epidural Anaesthesia on Myocardial Ischemia in Peripheral Vascular Surgery Emre Kavlak, Zerrin Sungur Ülke, Mukadder Orhan Sungur, Meltem Savran Karadeniz, Ahmet Kaya Bilge, Mert Şentürk, Emre Çamcı, Mehmet Tuğrul doi: 10.5222/GKDAD.2012.096 Pages 96 - 104 (1640 accesses) OBJECTIVE: Dexmedetomidine (dex) has beneficial effects on heart rate and provides adequate sedation in the perioperative period. We aimed to investigate the effects of dex added to epidural anaesthesia on myocardial ischemia and postoperative analgesic requirements in peripheral vascular surgery. METHODS: During surgery under epidural anaesthesia, patients were allocated in 2 groups. In group D, sedation was achieved with dex during surgery and in ICU for the first postoperative 24 hours. The second group (GM) received midazolam sedation for the time. Both drug infusions were titrated to achieve a target level of sedation. Epidural anaesthesia and postoperative analgesia were identical for two groups. Hemodynamic parameters and ECG analysis were recorded during surgery and in ICU for 48 hours. Troponin levels were measured at the beginning and postoperative 4th, 8th, 24th, 36th, 48th hours. Visual analogue scale (VAS) and postoperative analgesic requirements were also noted. RESULTS: In GD, heart rate was slower than GM at all times. Duration of ischemic episodes were significantly shorter in GD than GM). Troponin levels were found to be significantly lower in GD at postoperative 24th, 36th, 48th hours (p<0.05). Analgesic consumption was significantly lower in GD than in GM at postoperative 24th and 48th hours (p<0.01). CONCLUSION: Dex combined to epidural anaesthesia ensured adequate sedation as midazolam; moreover dex infusion was associated with lower heart rate, reduced troponin levels and reduced analgesic requirements. These effects persisted even after discontinuation of dex infusion. |
| CASE REPORT | |
| 4. | Management of Anesthesia for noncardiac surgery in pediatric patient with isolated persistent patent ductus arteriosus Yasemin Işık, Muhammed Bilal Çeğin, Uğur Göktaş, Onur Palabıyık, İsmail Katı doi: 10.5222/GKDAD.2012.105 Pages 105 - 108 (1591 accesses) The main goals for a safe method of anesthesia during noncardiac surgery in pediatric patients with congenital cardiac anomaly are evaluation of patient’s preoperative condition, maintaining optimal oxygenation according to the pathophysiology of accompanying cardiac disease and keeping of cardiac stability. In this report, we aimed to discuss both the method of anesthesia that we applied to a pediatric case having patent ductus arteriosus and what shoud be done for a safe anesthetic method in patients with patent ductus arteriosus. |
| 5. | Fatal Venous Air Embolism After Hysteroscopy Mustafa Said Aydoğan, Mehmet Ali Erdoğan, Hüseyin Konur, Türkan Toğal doi: 10.5222/GKDAD.2012.109 Pages 109 - 111 (2082 accesses) Hysteroscopy for diagnosis and treatment of intrauterine pathologies such as rapid postoperative recovery and lower morbidity due to provide the "gold standard" is considered as a technical. Although hysteroscopy is a safe and easy method of minimally invasive procedures used during the procedure, particularly operative hysteroscopy brings along many risks that anesthetists should consider about. In this case, we presented venous air embolism developed after the operative hysteroscopy, and aimed to draw attention to the management of these complications. |