ISSN 1305-5550 | e-ISSN 2548-0669
Göğüs Kalp Damar Anestezi ve Yoğun Bakım Derneği Dergisi [GKD Anest Yoğ Bak Dern Derg]
GKD Anest Yoğ Bak Dern Derg. 2023; 29(3): 148-153 | DOI: 10.14744/GKDAD.2023.38243

Comparison of Modified and Conventional Ultrafiltration in Pediatric Patients Undergoing Open-Heart Surgery: Single-Center, Early Outcomes

Fatih Özdemir1, Onur Doyurgan2
1Department of Pediatric Cardiovascular Surgery, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, İstanbul, Türkiye
2Department of Pediatric Cardiovascular Surgery, Gazi Yaşargil Training and Research Hospital, Diyarbakır, Türkiye

Objectives: The use of cardiopulmonary bypass (CPB) in pediatric patients during open-heart surgery is associated with excessive inflammation, fluid leakage, and end-organ dysfunction. To reduce these effects, various ultrafiltration (UF) techniques are utilized. In this study, we aimed to compare the effect and early outcomes of modified UF (MUF) and conventional UF (CUF) in infants undergoing pediatric cardiac surgery.
Methods: A total of 232 infants who underwent open-heart surgery with CPB between February 2018 and January 2020 were retrospectively reviewed. Fifty-six patients weighing ≤15 kg with a history of any UF technique use were included. Patients were stratified into CUF (n=23) and MUF (n=33) groups. Preoperative patient characteristics and intraoperative and postoperative outcomes were recorded.
Results: The MUF group had a lower patient size (height, weight, and body surface area), with no statistical difference. Intraoperative parameters (CPB and cross-clamp time) and prime solution components were similar between groups. MUF significantly shortened the mechanical ventilation (MV) time (p=0.048) in contrast to intensive care unit stay, which showed no significant difference.
Conclusion: In our series, we demonstrated that the MV duration was shorter in the MUF group, which is consistent with prior literature. Additionally, although the lower weight of the patients in the MUF group showed no statistical significance, early hemodynamic effect and low mortality in this group support the potential benefits of MUF. With its cost-efficiency and early benefits, MUF is an effective UF method with a good safety profile, especially in low-weight infants.

Keywords: Cardiopulmonary bypass, ultrafiltration, ventilator weaning

Fatih Özdemir, Onur Doyurgan. Comparison of Modified and Conventional Ultrafiltration in Pediatric Patients Undergoing Open-Heart Surgery: Single-Center, Early Outcomes. GKD Anest Yoğ Bak Dern Derg. 2023; 29(3): 148-153

Sorumlu Yazar: Fatih Özdemir, Türkiye
Makale Dili: İngilizce
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