Clinical Effects of Different Rocuronium Doses Used in Pediatric Rigid Bronchoscopy

INTRODUCTION: The bronchoscopy employed for the diagnostic and therapeutic purposes in the children admitting as a result of foreign body aspiration is performed with general anesthesia. In our study, we aimed to compare clinical efficacy and perioperative adverse adverse effects (broncoscophy, body movement, laryngospasm, bronchospasm, hypoxemia) by using rocuronium in varying doses in our pediatric patients who underwent rigid bronchoscopy.
METHODS: Pediatric patients who were subjected to rigid bronchoscopy were included in a retrospective study. The patients receiving 0.3 mg/kg (ED95) of rocuronium were included in Group I, 0.45 mg/kg (1.5 x ED95) in Group II and 0.6 mg/kg (2 x ED95) in Group III. The patients were evaluated in terms of duration of anesthesia, duration of bronchoscopy, body movement, additional drugs and development of complications.
RESULTS: Total 60 patients, 19 female and 41 male, with age in the range of 6 months-6 years were included in the study. The duration of anesthesia was longer in Group III than the other two groups. When the groups were compared with regard to body movement, bronchospasm, laryngospasm and hypoxemia during the bronchoscopy, the adverse events in Group I were found to be significantly different. Anesthesia duration and adverse effects were significantly less in Group II.
DISCUSSION AND CONCLUSION: In our study is used to different rocuronium doses for pediatric rigid bronchoscopy. We consider that the dose of 0.45 mg/kg rocuronium resulted in rapid relaxation and safe ventilation in the pediatric rigid bronchoscopy patients.

Pediyatrik Rijit Bronkoskopide Uygulanan Farklý Rokuronyum Dozlarýnýn Klinik Etkileri

GÝRÝÞ ve AMAÇ: Yabancý cisim aspirasyonu ile baþvuran çocuklarda taný ve tedavi için uygulanan bronkoskopi genel anestezi altýnda yapýlmaktadýr. Biz burada rijit bronkoskopi yapýlan çocuk hastalarýmýzda rokuronyumu deðiþen dozlarda kullanarak en ideal ve güvenli dozu belirlenmeyi amaçladýk.
YÖNTEM ve GEREÇLER: Yabancý cisim aspirasyon nedeni ile baþvuran ve rijid bronkoskopi yapýlan çocuk hastalar çalýþmaya dahil edildi. 60 çocuk hastanýn 19 kýz, 41 erkek yaþlarý 6 ay-6 yaþ arasýnda retrospektif olarak çalýþmaya alýndý. Rocuronium 0.3 mg/kg (ED 95) alan hastalar Group I, rocuronium 0.45 mg/kg (1.5 x ED95) Group II, rocuronium 0.6 mg/kg (2xED95) alanlarda Group III olarak gruplandýrýldý. Hastalar anestezi süresi, bronkoskopi süresi, vücut hareketliliði, ek ilaçlar ve komplikasyon geliþimi açýsýndan deðerlendirildi.
BULGULAR: Anestezi süresi grup III’de diðer gruplara göre daha uzundu. Bronkoskopi uygulamasýnda vücut hareketliliði, bronkospazm, laringospazm ve hipoksemi açýsýndan gruplar karþýlaþtýrýldýðýnda Grup I’ de yan etkiler anlamlý olarak farklý bulundu. Grup II' de anestezi süresi ve advers etkiler anlamlý olarak az bulundu.
TARTIÞMA ve SONUÇ: Çalýþmamýzda pediatrik rijit bronkoskopi için farklý roküronyum dozlarý kullanýlmýþtýr. Pediyatrik rijit bronkoskopi hastalarýnda roküronyum dozunun 0,45 mg / kg ile hýzlý kas gevþemesi ve güvenli ventilasyonla yapýlabileceðini düþünmekteyiz.