Myasthenia Gravis and Sugammadex Use

Myasthenia gravis is a muscle disease which results from autoimmune destruction of the nicotinic acetylcholine receptors. Patients with myasthenic has resistance to depolarizing muscle relaxants and usually increased sensitivity to nondepolarizing relaxants. A new agent sugammadex binds to steroid structured rocuronium and vecuronium and vanishes their affects.In this article presented usage of sugammadex for patients who are planned;one adult and one pediatric, timectomy.

Miyastenia Gravis ve Sugammadeks Kullanýmý

Myastenia gravis, nikotinik asetilkolin reseptörlerinin otoimmün yýkýmý sonucu geliþen bir kas hastalýðýdýr. Myastenik hastalarda depolarizan kas gevþeticilere genellikte direnç ve nondepolarizan kas gevþeticilere ise duyarlýlýkta artýþ söz konusudur. Yeni bir ajan olan sugammadeks steroid yapýdaki roküronyum ve veküronyumu baðlayarak, etkilerini ortadan kaldýrýr. Bu makalede roküronyum kullanýlan biri eriþkin diðeri pediatrik timektomi planlanan iki myastenik hastada kas gücünün geri dönüþümünü saðlamak için sugammadeks kullanýmý sunulmuþtur.