Effects of the Anesthesia Type on Hematological Parameters in Coronary Artery Bypass Grafting

Objectives: This study evaluated the effects of sevoflurane-based inhalation anesthesia and propofol-based total intravenous anesthesia on hematological parameters in coronary artery bypass grafting (CABG).
Methods: In this study, 125 patients who underwent elective on-pump CABG between November 2021 and April 2022 were retrospectively analyzed. Patients aged 35–80 years with an ejection fraction of ≥25% were included. The patients were separated into two groups: The sevoflurane group (Group SEVO) and the total intravenous anesthesia group (Group TIVA). Patient characteristics, operative clinical data, and preoperative and postoperative hematological parameters: [white blood cell (WBC) count, red cell distribution width (RDW), neutrophil/lymphocyte ratio (NLR)] were analyzed. Results: The mean age of the patients was 62.0±8.7 years. Group SEVO comprised 70 patients, and Group TIVA comprised 55 patients. Significant increases in postoperative WBC count, RDW, and NLR values were observed in both groups. No statistically significant differences in WBC count, RDW, and NLR values were observed between the two groups (p>0.05).
Conclusion: The effects of sevoflurane-based inhalation anesthesia or propofol-based total intravenous anesthesia on WBC count, RDW, and NLR values among patients undergoing elective on-pump CABG were similar.